The presentation will discuss the “Implementation of ‘Integrated Computational Materials Engineering’ or ‘ICME’ towards Managing the Fatigue Life of Components and Assemblies”. ICME combines computational modeling and materials engineering, and considers materials at multiple length scales, processes that produce these materials and the properties to predict and optimize the performance of components. VEXTEC characterizes materials at the microstructural level and uses its Virtual Life Management®  (VLM®) technology to understand material damage, flaw initiation and crack propagation towards estimating fatigue life in components and assemblies subject thermal / mechanical cyclic loads. The talk will discuss VLM in the context of industry recognized structural design philosophies: Safe Life and Damage Tolerance.